高蓝

1.简介

       高蓝,男,理学博士,校聘副教授,硕士研究生导师。2017年至今在安徽医科大学公共卫生学院卫生毒理学系工作,研究方向主要为发育和生殖毒理学。现任中华预防医学会自由基预防医学专委会青年委员、中华预防医学会环境卫生分会青年委员、安徽省预防医学会卫生毒理专委会委员、中国毒理学会会员。目前主持国家自然科学基金青年基金、安徽省自然科学基金青年项目、安徽省高等学校自然科学研究项目重点项目、安徽医科大学基础与临床合作研究提升计划、安徽医科大学博士科研资助基金、安徽医科大学校科研基金各1项,参与国自然重大项目、面上项目多项。指导本科生国家级“大学生创新训练计划”1项。曾获安徽省教学成果三等奖、安徽医科大学“优秀教师”、安徽医科大学公共卫生学院“先进个人”、安徽医科大学公共卫生学院课程思政竞赛一等奖、安徽医科大学公共卫生学院青年教师教学基本功竞赛三等奖。

2.教育经历

2012/09-2016/12,中科院昆明植物研究所植物化学与西部植物资源持续利用

国家重点实验室,药物化学,博士

2013/12-2015/10,中科院长春应化所电分析化学国家重点实验室,客座

2009/09-2012/06,南京农业大学与中科院昆明动物所联培,动物学,硕士

2004/09-2008/06,安徽农业大学,生物科学,学士

3.发表论文

1) Li J#, Gao L#(高蓝), Zhu BB, Lin ZJ, Chen J, Lu X, Wang H, Zhang C, Chen YH, Xu DX. Long-term 1-nitropyrene exposure induces endoplasmic reticulum stress and inhibits steroidogenesis in mice testes.Chemosphere, 2020; 251:126336. (#并列第一作者)

2)Gao L(高蓝)Chen JGao JWang HD*Xiong WY*. Super-resolution microscopy reveals the reorganization of GLUT4 on plasma membrane regulated by insulin resistance. Journal of cell science, 2017; 130 (2): 396-405 (*共同通讯作者)

3)Zhang ZY#Gao L#(高蓝)Shen CBRong MQ, Yan XWLai R. A potent anti-thrombosis peptide (vasotab TY) from horsefly salivary glandsInternational Journal of Biochemistry & Cell Biology, 2014; 54: 83–88. (#并列第一作者)

4)Kong QH#Gao L#(高蓝)Niu YFGongpan PCLi Y*Xiong WY*. RACK1 is required for adipogenesisAmerican Journal of Physiology-Cell Physiology, 2016; 311 (5): C831. (#并列第一作者) (*共同通讯作者)

5)Xiong YW#, Xu XF#, Zhu HL#, Cao XL, Yi SJ, Shi XT, Zhu KH, Nan Y, Zhao LL, Zhang C, Gao L(高蓝), Chen YH, Xu DX*, Wang H*. Environmental exposure to cadmium impairs fetal growth and placental angiogenesis via GCN-2-mediated mitochondrial stress.J Hazard Mater, 2020; 401:123438. (#并列第一作者) (*共同通讯作者)

6)Shi XT#, Zhu HL#, Xiong YW, Liu WB, Zhou GX, Cao XL, Yi SJ, Dai LM, Zhang C, Gao L(高蓝), Xu DX, Wang H. Cadmium down-regulates 11β-HSD2 expression and elevates active glucocorticoid level via PERK/p-eIF2α pathway in placental trophoblasts. Chemosphere, 2020; 254:126785. (#并列第一作者)

7)Wang B#, Xu S#, Lu X, Ma L, Gao L(高蓝), Zhang SY, Li R, Fu L, Wang H, Sun GP, Xu DX. Reactive oxygen species-mediated cellular genotoxic stress is involved in 1-nitropyrene-induced trophoblast cycle arrest and fetal growth restriction. Environ Pollut, 2020; 260:113984. (#并列第一作者)

8)Lu X#, Tan ZX#, Wang B, Li J, Hu B, Gao L(高蓝), Zhao H, Wang H, Chen YH*, Xu DX*. Maternal 1-nitropyrene exposure during pregnancy increases susceptibility of allergic asthma in adolescent offspring. Chemosphere, 2020; 243:125356. (#并列第一作者) (*共同通讯作者)

9)Xiong YW#, Zhu HL#, Nan Y, Cao XL, Shi XT, Yi SJ, Feng YJ, Zhang C, Gao L(高蓝), Chen YH, Xu DX*, Wang H*. Maternal cadmium exposure during late pregnancy causes fetal growth restriction via inhibiting placental progesterone synthesis. Ecotoxicol Environ Saf, 2020; 187:109879. (#并列第一作者) (*共同通讯作者)

10)Nan Y#, Yi SJ#, Zhu HL, Xiong YW, Shi XT, Cao XL, Zhang C, Gao L(高蓝), Zhao LL, Zhang J, Xu DX*, Wang H*. Paternal cadmium exposure increases the susceptibility to diet-induced testicular injury and spermatogenic disorders in mouse offspring. Chemosphere, 2019; 246:125776. (#并列第一作者) (*共同通讯作者)

11)Zhu HL#, Xu XF#, Shi XT, Feng YJ, Xiong YW, Nan Y, Zhang C, Gao L(高蓝), Chen YH, Xu DX, Wang H. Activation of autophagy inhibits cadmium-triggered apoptosis in human placental trophoblasts and mouse placenta. Environ Pollut, 2019; 254:112991. (#并列第一作者)

12)Chen W, Gao XX, Ma L, Liu ZB, Li L, Wang H, Gao L(高蓝), Xu DX*, Chen YH*. Obeticholic Acid Protects against Gestational Cholestasis-Induced Fetal Intrauterine Growth Restriction in Mice. Oxid Med Cell Longev, 2019; 2019:7419249.(*共同通讯作者)

13)Xu S, Song J, Zhang ZH, Fu L, Gao L(高蓝), Xie DD, Yu DX, Xu DX*, Sun GP*. The Vitamin D status is associated with serum C-reactive protein and adhesion molecules in patients with renal cell carcinoma. Sci Rep, 2019; 9(1):16719. (*共同通讯作者)

14)Song J#, Xu S#, Zhang ZH, Chen YH, Gao L(高蓝), Xie DD, Sun GP, Yu DX*, Xu DX*. The correlation between low vitamin D status and renal interleukin-6/STAT3 hyper-activation in patients with clear cell renal cell carcinoma. Steroids, 2019; 150:108445. (#并列第一作者) (*共同通讯作者)

15)Song YP#, Chen YH#, Gao L(高蓝), Wang P, Wang XL, Luo B, Li J, Xu DX. Differential effects of high-fat diets before pregnancy and/or during pregnancy on fetal growth development. Life Sci, 2018; 212:241-250. (#并列第一作者)

16)Chen JLLiu TZGao JGao L(高蓝)Zhou LLCai MJShi YJiang JGTong T*Wang HD*. Variation in carbohydrates between cancer and normal cell membranes revealed by super-resolution fluorescence imagingAdvanced Science, 2016; 3(12) (*共同通讯作者)