张君
2021-02-12



1.简介

理学博士。学术兼职:中国毒理学会会员,安徽省环境诱变剂学会理事。专业与教材建设:参编《食品毒理学》、《生活中的毒物》教材。教学工作:主要承担本科生《毒理学基础》、《卫生毒理学》、《药物毒理学》及《食品毒理学》的理论及实验教学工作,参与研究生《医学分子生物标志》、《分子医学实验技术与方法》的教学工作。获得荣誉:安徽医科大学2018年度十佳科技新星,安徽医科大学公共卫生学院“先进个人”称号,2019年公共卫生学院青年教师教学基本功暨“课程思政”竞赛二等奖, 2017年公共卫生学院青年教师教学基本功竞赛三等奖等。科学研究:主持国家自然科学基金青年项目1项、安徽省自然科学基金青年项目1,安徽省教育厅高校自然科学研究重点项目1。研究方向为生殖毒理学。


2.教育经历

2007/09-2014/01,中国科学院动物研究所,发育生物学专业,硕博连读研究生

2003/09-2007/07,河南大学,生物技术专业,本科生


3.工作经历

2014/07-----至今,安徽医科大学,公共卫生学院,讲师


4.主持科研项目

[1]国家自然科学基金青年项目,81602880,内质网IRE1通路介导镉致小鼠卵巢颗粒细胞凋亡的作用机制,2017/01-2019/1218万元,结题,主持人。

[2]安徽省自然科学基金青年项目,1708085QH185,镉致小鼠卵巢颗粒细胞凋亡的作用机制研究,2017/07-2019/068万元,结题,主持人。

[3]安徽省教育厅高校自然科学研究重点项目,KJ2020A0210,内质网应激在镉致小鼠卵泡发育异常及卵巢早衰中的作用,2021/01-2022.12, 6万元,主持。


5.代表性SCI论文

[1]Jun Zhang #, Yan Wang #, Lin Fu, Bo Wang, Yanli Ji, Hua Wang, Dexiang Xu*, Chronic cadmium expo-sure induced hepatic cellular stress and inflammation in aged female mice, Journal of Applied Toxicology, 2019, 39(3):498-509. (IF: 3.065)

[2]Jun Zhang#, Yan Wang#, Lin Fu, Yujie Feng, Yanli Ji,Hua Wang, Dexiang Xu. Subchronic cadmium exposure upregulates the mRNA level of genes associated to hepatic lipid metabolism in adult female CD1 mice. Journal of Applied Toxicology, 2018, 38(7):1026-1035. (IF: 3.065)

[3]Fei Gao#*#, Jun Zhang#, Xiaona Wang, Junling Yang, Dahua Chen, Vicki Huff(*), Yixun Liu*. Wt1 functions in ovarian follicle development by regulating granulosa cell differentiation. Human Molecular Genetics. 2014, 23(2): 333-341. (IF: 5.34)

[4]Xiaona Wang#, Zesong Li #, Yu Ren #, Tao Jiang #, Yaqing Wang, Min Chen, Jun Zhang, Jianxiu Hao, Yanbo Wang, Rina Sha, Yi Huang, Xiao Liu, Jingchu  Hu, Guangqing Sun, Honggang Li, Chengliang Xiong, Jun Xie, Zhimao Jiang, Zhiming Cai, Jun Wang, Jian Wang, Vicki Huff*,Yao Ting Gui*, Fei Gao*. The Wilms Tumor Gene, Wt1, Is Critical for Mouse Spermatogenesis via Regulation of Sertoli Cell Polarity and Is Associated with Non-Obstructive Azoospermia in Humans, PLoS Genetics, 2013, 9(8): e1003645. (IF: 6.66)

[5]Huidan Wang, Guangyu Li, Jun Zhang, Fei Gao, Weiping Li, Yingying Qin*, Zijiang Chen*. Novel WT1 Missense Mutations in Han Chinese Women with Premature Ovarian Failure, Scientific Reports, 2015, 5: 13983. (IF: 4.26)

[6]Chunping Zhang, Junling Yang, Jun Zhang, Lei Li, Lin Huang, Shaoyang Ji, Zhaoyuan Hu, Fei Gao*, Yixun Liu*. Notch Signaling Is Involved in Ovarian Follicle Development by Regulating Granulosa Cell Proliferation, Endocrinology, 2011, 152(6): 2437-2447. (IF: 4.29)

[7]Lei Li, Shaoyang Ji, Junling Yang, Xixia Li, Jun Zhang, YangZhang, Zhaoyuan Hu, Yixun Liu*. Wnt/β-catenin signaling regulates follicular development by modulating the expression of Foxo3a signaling components, Molecular and Cellular Endocrinology, 2014, 382(2): 915-925. (IF: 3.75)

[8]Suren Chen, Min Chen, Xiaona Wang, Jun Zhang, Qing Wen, Shaoyang Ji, Qiaosong Zheng, Fei Gao*Yixun Liu*. The Wilms Tumor Gene, Wt1, Maintains Testicular Cord Integrity by Regulating the Expression of Col4a1 and Col4a2, Biology of Reproduction, 2013, 88(3):56. (IF: 3.47)

[9]Shaoyang Ji, Jianxiu Hao, Lei Li, Jun Zhang, Qiaosong Zheng, Xixia Li, Xiaona Wang, Chunsheng Han, Fei Gao*, Yixun Liu*. Expression of Inhibin-Alpha Is Regulated Synergistically by Wilms' Tumor Gene 1 (Wt1) and Steroidogenic Factor-1 (Sf1) in Sertoli Cells, PLos One, 2013, 8(1):e53140. (IF: 2.80)

[10]Hua Wang#*, Lulu Yang #, Yanli Ji, Yuanhua Chen, Jun Hu, Cheng Zhang, Jun Zhang, Dexiang Xu*. Different fixative methods influence histological morphology and TUNEL staining in mouse testes, Reproductive Toxicology, 2016, 60: 53-61. (IF: 2.34)