蔡亦红，副教授，卫生检验和检疫学系，公共卫生学院，安徽医科大学。

教育经历

2010 – 2014                     免疫学，博士学位，安徽医科大学

2003 – 2006                     微生物学，硕士学位，安徽医科大学

1998 – 2003                     临床医学，学士学位，皖南医学院

工作经历

2018.9-2019.9  访问学者，Oakland University，Michigen，美国

2015.6-2015.12 访问学者，Immunology Frontier Research Center, Osaka University, 日本

2006-present  副教授，卫生检验和检疫学系，公共卫生学院，安徽医科大学，中国

发表论著(* 通讯作者)

1. Li Y, Poppoe F, Chen J, Yu L, Deng F, Luo Q, Xu Y, Cai Y*, Shen J*. Macrophages Polarized by expression of Toxogra15Ⅱ inhibit growth of hepatic carcinoma，Frontiers in Immunology.(2017);8:137.

2. Cai Y, Shen J*. Modulation of host immune responses to Toxoplasma gondii by microRNAs，Parasite Immunology.(2017);39:e12417.

3. Zhang X, Su R, Cheng Z, Zhu W, Li Y, Wang Y, Du J, Cai Y, Luo Q, Shen J, Yu L. A mechanistic study of Toxoplasma gondii ROP18 inhibiting differentiation of C17.2 neural stem cells. Parasites & Vectors. (2017),23;10(1):585.

4. Gan X, Zhang X, Cheng Z, Chen L, Ding X, Du J, Cai Y, Luo Q, Shen J, Wang Y, Yu L. Toxoplasma gondii inhibits differentiation of C17.2 neural stem cells through Wnt/β-catenin signaling pathway.Biochem Biophys Res Commun. (2016); 22;473(1):187-193.

5. Zhang Q, He L, Kong L, Zhang Y, Chen H, An R, Wang L, Wang W, Xu X, Zhang A, Cai Y, Li M, Wen H, Luo Q, Shen J. Genotype-Associated Arginase 1 Expression in Rat Peritoneal Macrophages Induced by Toxoplasma gondii.J Parasitol. (2015 );101(4):418-23. 

6. Lanting K, Qian Z, Jing Chao, Huiqin W, Yihua Z, He Chen, Faustina P, Aimei Z, Xiucai X, Yihong C, Min L, Qingli Luo, Linjie Z, Jilong S*. Polarization of macrophages induced by Toxoplasma gondii and its impact on abnormal pregnancy in rats. Acta Tropica. (2015)143:1-7. 

7. Yi-Hong Cai, He Chen, Xu-Wei Mo, Yuan-Yuan Tang, Xiucai Xu, Aaimei Zhang, Zhao-Rong Lun, Fang-Li Lu,Yong Wang, and Ji-Long Shen*. Toxoplasma gondii inhibits apoptosis via a novel STAT3-miR-17–92-Bim pathway in macrophages. Cellular Signalling. (2014)26:1204-1212. 

8. Yi-Hong Cai, He Chen, Lei Jin, Yibo You and Jilong Shen*. STAT3-dependent transactivation of miRNA genes following Toxoplasma gondii infection in macrophage. Parasites & Vectors. (2013):356-365. 

9. Yi-hua Zhang, He Chen, Ying Chen, Lu Wang, Yi-hong Cai, Min Li, Hui-qin Wen, Jian Du, Ran An, Qing-li Luo, Xue-long Wang, Zhao-Rong Lun, Yuan-hong Xu and Ji-long Shen*, Activated microglia contribute to neuronal apoptosis in Toxoplasmic encephalitis. Parasites & Vector.( 2014)7:372-383. 

10. Huo XX, Wang L, Chen ZW, Chen H, Xu XC, Zhang AM, Song XR, Luo QL, Xu YH, Fu Y, Wang H, Du J,Cai YH, Lun ZR, Lu FL, Wang Y, and Shen JL*. Preventive effct of pidotimod on reactivated toxoplasmosis in mice.Parasitol Research. (2013)112:3041-3051.

11. Liu TT, Zhang Q, Liu LL, Xu XC, Chen H, Wang H, Kong LT, Wang WW, Cai YH, Zhang AM, Li M, Yu L, Du J, Wang XL, Luo QL, Lun ZR, Wang Y, andShen JL*. Trophoblast apoptosis through polarization of macrophages induced by Chinese Toxoplasma gondii isolates with different virulence in pregnant mice. Parasitol Research. (2013)112:3019-3027.

12. Zhang AM, Shen Q, Li M, Xu XC, Chen H,Cai YH, Luo QL, Chu DY, Yu L, Du J, Lun ZR, Wang Y, Sha Q and Shen JL*. Comparative studies of macrophage-biased responses in mice to infection with Toxoplasma gondii ToxoDB #9 strains of different virulence isolated from China.Parasites and Vectors. (2013)6:308-318. 

13. Liu L, Liu T, Yu L,Cai Y, Zhang AM, Xu XC, Luo QL, Hu YS, Song WJ, Lun ZR, Lu FL, Wang Y, and Shen JL*, Rrop2186-533:A novel peptide antigen for detection of IgM antibodies against Toxoplasma gondii. Foodborne Pathogens & Disease. (2012)9:7-12.

主持基金：

1. 国家自然科学基金面上项目 (NSFC)(No: 81572801), Antitumor effect of Toxoplasma polymorphic effector GRA15Ⅱ in HCC through regulation of macrophage polarization, 2016.1-2019.12 (ongoing)

2. 国家自然科学青年基金(NSFC)(No: 81101272), Mitochondrial apoptosis through a novel STAT3-miR-17s-Bim pathway in Toxoplasma infected host cells 2012.1-2014.12. (completed)